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Beitragstitel 8th Edition TNM Staging System: What changes to expect in cancer of the oral cavity?
Beitragscode O04
Autor:innen
  1. Yanic Ammann Kantonsspital St. Gallen Präsentierende:r
  2. Domenic Vital Zentrum für Kopf-Hals-Chirurgie
  3. Grégoire Morand Universitätsspital Zürich
  4. Martina Anja Broglie-Däppen Universitätsspital Zürich
  5. Sandro J. Stöckli Kantonsspital St. Gallen
  6. Gerhard Frank Huber Klinik Hirslanden
Präsentationsform Vortrag
Themengebiete
  • SGORL FV 2019
Abstract-Text Aim: In the 8th Edition of the AJCC/TNM staging system, depth of infiltration (DOI) was introduced as a criterion for T-Stage in squamous cell carcinoma of the oral cavity (SCCOC). This leads to an upstaging of ~15-20% of patients; this in contrast to other tumour entities, where the 8th edition also leads to a downstaging (well differentiated thyroid cancer).
Material and Methods: We analyzed the combined sentinel patient cohorts of St. Gallen and Zurich between 2003 and 2017 and staged the groups according to the 7th and the 8th edition and compared the outcomes between the groups. The sentinel cohort was chosen since the comparable N-Status (clinically N0) and available histopathology in all patients (measurement of DOI).
Results: 180 patients were included in the study. According to the 7th edition, 120 were staged T1 and 60 T2; according the new classification the same cohort was staged: 95 T1, 75 T2 and 10 T3. As expected, in the never classification, the T1 tumours showed improved disease specific and overall survival, while the T2 Kaplan Meier curve remained comparable with the one staged by the 7th edition, while the T3 showed a poor prognosis.
Conclusions: The new staging system for SCCOC, including the DOI, shows a more differentiated picture about the expected outcomes than the antecedent one.